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1

A two-step procedure for purification of papain from extract of papaya latex

David E. Burke, Sidney D. Lewis, Jules A. Shafer

Journal:

Archives of Biochemistry and Biophysics

Year:

1974

Language:

english

File:

PDF, 1.68 MB

english, 1974

2

Pertubations in the Free Energy and Enthalpy of Ionization of Histidine-159 at the Active Site of Papain As Determined by Fluorescence Spectroscopy

Johnson, Frederick, Lewis, Sidney, Shafer, Jules

Journal:

Year:

1981

Language:

english

File:

PDF, 916 KB

english, 1981

3

Modification of the reactivity of a small molecule by reversible association with a synthetic polymer. Inhibition of the hydrolysis of cationic esters by polyanions

Herbert Morawetz, Jules A. Shafer

Journal:

Year:

1963

Language:

english

File:

PDF, 381 KB

english, 1963

4

Phosphorylation of the insulin receptor by casein kinase I

Polygena T. Tuazon, Dennis T. Pang, Jules A. Shafer, Jolinda A. Traugh

Journal:

Journal of Cellular Biochemistry

Year:

1985

Language:

english

File:

PDF, 652 KB

english, 1985

5

The interaction of papain and certain S-alkylated papains with dextran and polyacrylamide gels used in thin-layer gel chromatography

Edward T. Maggio, Jules A. Shafer

Journal:

Analytical Biochemistry

Year:

1973

Language:

english

File:

PDF, 184 KB

english, 1973

6

An immobilized naphthylamide substrate for proteinases with tryptic-like specifleity

Deborah L. Higgins, Jules A. Shafer

Journal:

Analytical Biochemistry

Year:

1977

Language:

english

File:

PDF, 417 KB

english, 1977

7

A convenient lactic dehydrogenase-coupled assay for determining pyridoxal 5′-phosphate in plasma

Stephen T. Worland, Jules A. Shafer

Journal:

Analytical Biochemistry

Year:

1980

Language:

english

File:

PDF, 715 KB

english, 1980

8

Amide and α-keto carbonyl inhibitors of thrombin based on arginine and lysine: Synthesis, stability and biological characterization

Stephen F. Brady, John T. Sisko, Kenneth J. Stauffer, Christiana D. Colton, Howard Qiu, Sidney D. Lewis, Assunta S. Ng, Jules A. Shafer, Michael J. Bogusky, Daniel F. Veber, Ruth F. Nutt

Journal:

Bioorganic & Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.29 MB

english, 1995

9

Identification and SAR for a selective, nonpeptidyl thrombin inhibitor

Adel M. Naylor-Olsen, Gerald S. Ponticello, S.Dale Lewis, Anne M. Mulichak, Zhonguo Chen, Charles N. Habecker, Brian T. Phillips, William M. Sanders, Thomas J. Tucker, Jules A. Shafer, Joseph P. Vacca

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 382 KB

english, 1998

10

Cardiovascular chemotherapy: anticoagulants

Journal:

Current Opinion in Chemical Biology

Year:

1998

Language:

english

File:

PDF, 917 KB

english, 1998

11

Catalytically competent human and bovine ζ-thrombin and chimeras generated from unfolded polypeptide chains

Sidney D. Lewis, Diane V. Brezniak, Jules A. Shafer, John W. Fenton II

Journal:

Protein Science

Year:

1992

Language:

english

File:

PDF, 915 KB

english, 1992

12

Design of antithrombotic agents: An introduction

Robert J. Gould, Jules A. Shafer

Journal:

Perspectives in Drug Discovery and Design

Year:

1994

Language:

english

File:

PDF, 253 KB

english, 1994

13

Alkaline proteases from the gut fluids of detritus-feeding larvae of the crane fly, Tipula abdominalis (say) (diptera, tipulidae)

Baldev R. Sharma, Michael M. Martin, Jules A. Shafer

Journal:

Insect Biochemistry

Year:

1984

Language:

english

File:

PDF, 749 KB

english, 1984

14

A facile system for construction of HSV-1 variants: site directed mutation of the UL26 protease gene in HSV-1

R.Bruce Register, Jules A. Shafer

Journal:

Journal of Virological Methods

Year:

1996

Language:

english

File:

PDF, 1.31 MB

english, 1996

15

Isolation of a catalytically competent phosphorylated tyrosine kinase from Rous sarcoma virus-induced rat tumor by immunoadsorption to and hapten elution from phosphotyrosine binding antibodies

Susan Whitehouse-Hills, Lawrence S. Argetsinger, Jules A. Shafer

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1990

Language:

english

File:

PDF, 1.15 MB

english, 1990

16

Intermediates in the Reaction Catalyzed by Glutamate Dehydrogenase

Eraldo Antonini, Emilia Chiancone, K. Lemone Yielding, Jules A. Shafer

Journal:

Year:

1972

Language:

english

File:

PDF, 437 KB

english, 1972

17

Binding of Reduced Cofactor to Glutamate Dehydrogenase

Jules A. Shafer, Emilia Chiancone, Letizia M. Vittorelli, Carla Spagnuolo, Bruce Mackler, Eraldo Antonini

Journal:

Year:

1972

Language:

english

File:

PDF, 539 KB

english, 1972

18

Kinetic parameters for the binding of p-nitrophenyl α-d-mannopyranoside to concanavalin A

Sidney D. Lewis, Jules A. Shafer, Irwin J. Goldstein

Journal:

Archives of Biochemistry and Biophysics

Year:

1976

Language:

english

File:

PDF, 628 KB

english, 1976

19

A support for affinity chromatography that covalently binds amino groups via a cleavable connector arm

Pratap Singh, Sidney D. Lewis, Jules A. Shafer

Journal:

Archives of Biochemistry and Biophysics

Year:

1979

Language:

english

File:

PDF, 1006 KB

english, 1979

20

A solid support for affinity chromatography that covalently binds thiol groups via a cleavable connector arm

Pratap Singh, Sidney D. Lewis, Jules A. Shafer

Journal:

Archives of Biochemistry and Biophysics

Year:

1980

Language:

english

File:

PDF, 586 KB

english, 1980

21

pK perturbations of nitrophenol-containing reporter groups at the active site of papain

Elva Mae Nicholson, Jules A. Shafer

Journal:

Archives of Biochemistry and Biophysics

Year:

1980

Language:

english

File:

PDF, 594 KB

english, 1980

22

A reagent for covalently attaching biotin to proteins via a cleavable connector arm

Catharine A. Mouton, Dennis Pang, C.V. Natraj, Jules A. Shafer

Journal:

Archives of Biochemistry and Biophysics

Year:

1982

Language:

english

File:

PDF, 764 KB

english, 1982

23

Relationship between the subunit structure of insulin receptor and its competence to bind insulin and undergo phosphorylation

Dennis T. Pang, Sidney D. Lewis, Baldev R. Sharma, Jules A. Shafer

Journal:

Archives of Biochemistry and Biophysics

Year:

1984

Language:

english

File:

PDF, 4.33 MB

english, 1984

24

Purification of the catalytically active phosphorylated form of insulin receptor kinase by affinity chromatography with O-phosphotyrosyl-binding antibodies

Dennis T. Pang, Baldev R. Sharma, Jules A. Shafer

Journal:

Archives of Biochemistry and Biophysics

Year:

1985

Language:

english

File:

PDF, 2.31 MB

english, 1985

25

Carbohydrate binding properties of the stinging nettle (Urtica dioica) rhizome lectin

Naoto Shibuya, Irwin J. Goldstein, Jules A. Shafer, Willey J. Peumans, Willem F. Broekaert

Journal:

Archives of Biochemistry and Biophysics

Year:

1986

Language:

english

File:

PDF, 829 KB

english, 1986

26

Effect of potassium ion on the phosphorus-31 nuclear magnetic resonance spectrum of the pyridoxal 5′-phosphate cofactor of Escherichia coli d-serine dehydratase

Christopher L. Kojiro, Michelle Marceau, Jules A. Shafer

Journal:

Archives of Biochemistry and Biophysics

Year:

1989

Language:

english

File:

PDF, 539 KB

english, 1989

27

Insulin stimulated protein phosphorylation in human plasma liver membranes: Detection of endogenous or plasma membrane associated substrates for insulin receptor kinase

JoséF. Caro, Jules A. Shafer, Simeon I. Taylor, S.M. Raju, Nichola Perrotti, Madhur K. Sinha

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 1.15 MB

english, 1987

28

γ-Secretase: characterization and implication for Alzheimer disease therapy

Min Xu, Ming-Tain Lai, Qian Huang, Jillian DiMuzio-Mower, José L Castro, Timothy Harrison, Alan Nadin, Joseph G Neduvelil, Mark S Shearman, Jules A Shafer, Stephen J Gardell, Yue-Ming Li

Journal:

Neurobiology of Aging

Year:

2002

Language:

english

File:

PDF, 298 KB

english, 2002

29

Kinetics of the conformational transition of poly(methacrylic acid) after changes of its degree of ionization

Bednar, Bohumil, Morawetz, Herbert, Shafer, Jules A.

Journal:

Year:

1985

Language:

english

File:

PDF, 615 KB

english, 1985

30

Effect of Fibrinogen and Ca2+ on the Thrombin-Catalyzed Proteolytic Event That Triggers Activation of Factor XIII

JULES A. SHAFER, SIDNEY D. LEWIS, TODD J. JANUS, LASZLO LORAND

Journal:

Annals of the New York Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 311 KB

english, 1986

31

Characterization of the extended carbohydrate binding site of concanavalin A: Specificity for interaction with the nonreducing termini of α-(1→2)-linked disaccharides

Taffy J. Williams, Louis D. Homer, Jules A. Shafer, Irwin J. Goldstein, Per J. Garegg, Hans Hultberg, Tommy Iversen, Rolf Johansson

Journal:

Archives of Biochemistry and Biophysics

Year:

1981

Language:

english

File:

PDF, 874 KB

english, 1981

32

Determining the extent of labeling for tetramethylrhodamine protein conjugates

David L. Meadows, Jules S. Shafer, Jerome S. Schultz

Journal:

Journal of Immunological Methods

Year:

1991

Language:

english

File:

PDF, 749 KB

english, 1991

33

Fibrinogen petoskey: Identification of a new dysfibrinogenemia characterized by altered release of fibrinopeptide A

Deborah L. Higgins, John A. Penner, Jules A. Shafer

Journal:

Thrombosis Research

Year:

1981

Language:

english

File:

PDF, 1022 KB

english, 1981

34

A thrombin assay based upon the release of fibrinopeptide a from fibrinogen: Definition of a new thrombin unit

Sidney D. Lewis, Jules A. Shafer

Journal:

Thrombosis Research

Year:

1984

Language:

english

File:

PDF, 731 KB

english, 1984

35

α-Thrombin within fibrin clots: Inactivation of thrombin by antithrombin-III

Michael C. Naski, Jules A. Shafer

Journal:

Thrombosis Research

Year:

1993

Language:

english

File:

PDF, 1.03 MB

english, 1993

36

Reactivity of small thiolate anions and cysteine-25 in papain toward methyl methanethiosulfonate

Roberts, David D., Lewis, Sidney D., Ballou, David P., Olson, Steven T., Shafer, Jules A.

Journal:

Year:

1986

Language:

english

File:

PDF, 874 KB

english, 1986

37

Effect of cysteine-25 on the ionization of histidine-159 in papain as determined by proton nuclear magnetic resonance spectroscopy. Evidence for a histidine-159-cysteine-25 ion pair and its possible role in catalysis

Lewis, Sidney D., Johnson, Frederick Allen, Shafer, Jules A.

Journal:

Year:

1981

Language:

english

File:

PDF, 497 KB

english, 1981

38

ROUND-UP Service Delivery

Brady, Stephen, Bruce, James, Singh, Satendra, Crouthamel, Ming-Chih, Holoway, Katharine M., Coburn, Craig, Vacca, Joseph P., Shafer, Jules A., Hazuda, Daria, Lai, Ming-Tain

Journal:

Reproductive Health Matters

Year:

2001

Language:

english

File:

PDF, 627 KB

english, 2001

39

P4-187 Development of BACE 1 inhibitors

Brady, Stephen, Bruce, James, Singh, Satendra, Crouthamel, Ming-Chih, Holoway, Katharine M., Coburn, Craig, Vacca, Joseph P., Shafer, Jules A., Hazuda, Daria, Lai, Ming-Tain

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 162 KB

english, 2004

40

Dissociation and association of the HIV-1 protease dimer subunits: Equilibria and rates

Darke, Paul L., Hall, Dawn L., Jordan, Susan P., Zugay, Joan A., Shafer, Jules A., Kuo, Lawrence C.

Journal:

Year:

1994

Language:

english

File:

PDF, 989 KB

english, 1994

41

Reconstitution of catalytically competent human .zeta.-thrombin by combination of .zeta.-thrombin residues A1-36 and B1-148 and an Escherichia coli expressed polypeptide corresponding to .zeta.-thrombin residues B149-259

Gan, Zhong Ru, Lewis, Sidney D., Stone, James R., Shafer, Jules A.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.22 MB

english, 1991

42

Isoprenoid diphosphate utilization by recombinant human farnesyl:protein transferase: Interactive binding between substrates and a preferred kinetic pathway

Pompliano, David L., Schaber, Michael D., Mosser, Scott D., Omer, Charles A., Shafer, Jules A., Gibbs, Jackson B.

Journal:

Year:

1993

Language:

english

File:

PDF, 851 KB

english, 1993

43

Potentiometric determination of ionizations at the active site of papain

Lewis, Sidney D., Johnson, Frederick A., Shafer, Jules A.

Journal:

Year:

1976

Language:

english

File:

PDF, 1.06 MB

english, 1976

44

Growth hormone promoted tyrosyl phosphorylation of growth hormone receptors in murine 3T3-F442A fibroblasts and adipocytes

Foster, Carol M., Shafer, Jules A., Rozsa, Frank W., Wang, Xueyan, Lewis, Sidney D., Renken, David A., Natale, Joanne E., Schwartz, Jessica, Carter-Su, Christin

Journal:

Year:

1988

Language:

english

File:

PDF, 3.40 MB

english, 1988

45

Identification and Characterization of Variants of Tick Anticoagulant Peptide with Increased Inhibitory Potency toward Human Factor Xa

Mao, Shi-Shan, Huang, Jin, Welebob, Carolee, Neeper, Michael P., Garsky, Victor M., Shafer, Jules A.

Journal:

Year:

1995

Language:

english

File:

PDF, 726 KB

english, 1995

46

Solution oligomerization of the rev protein of HIV-1: Implications for function

Cole, James L., Gehman, John D., Shafer, Jules A., Kuo, Lawrence C.

Journal:

Year:

1993

Language:

english

File:

PDF, 797 KB

english, 1993

47

Intramolecular Bifunctional Catalysis of Amide Hydrolysis

Morawetz, Herbert., Shafer, Jules.

Journal:

Journal of the American Chemical Society

Year:

1962

Language:

english

File:

PDF, 249 KB

english, 1962

48

Role of calcium ion in the generation of factor XIII activity

Hornyak, Thomas J., Shafer, Jules A.

Journal:

Year:

1991

Language:

english

File:

PDF, 2.08 MB

english, 1991

49

Regulation of the formation of factor XIIIa by its fibrin substrates

Lewis, Sidney D., Janus, Todd J., Lorand, Laszlo, Shafer, Jules A.

Journal:

Year:

1985

Language:

english

File:

PDF, 1.34 MB

english, 1985

50

Sensitivity of HIV-1 Reverse Transcriptase and Its Mutants to Inhibition by Azidothymidine Triphosphate

Carroll, Steven S., Geib, James, Olsen, David B., Stahlhut, Mark, Shafer, Jules A., Kuo, Lawrence C.

Journal:

Year:

1994

Language:

english

File:

PDF, 2.06 MB

english, 1994